| 产品详情 |
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| Antigenic Specificity | alpha Adaptin |
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| Clone | AC1-M11 |
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| Host Species | Mouse |
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| Reactive Species | amphibian, bovine, chicken, human, mouse, nonhuman primate, porcine, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay dependent, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | alpha Adaptin Monoclonal Antibody (AC1-M11). Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Src homologous and collagen-like (Shc) and epidermal growth factor ( |
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| Immunogen | n/a |
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| Other Names | AP2 |
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| Gene, Accession # | Entrez: 100520250, 11771, 160, 308578, 784636; Uniprot: O95782, P17426 |
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| Catalog # | MA3-061 |
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| Price | |
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| Order / More Info | alpha Adaptin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10551776, 12093727, 12704659, 12944396, 14528017, 1607381, 16999739, 17463283, 18939958, 19201926, 20133374, 20519538, 22099461, 22885770, 27392092, 29062065 |
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