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| Product Name | Recombinant Murine Sonic Hedgehog (Shh) Protein |
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| Description | Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). The biologically active form of Hh molecules is obtained by autocatalytic cleavage of their precursor proteins and corresponds to approximately the N-terminal one half of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can substitute for each other in experimental systems. Recombinant murine Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the naturally occurring chemically modified Cys residue. |
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| Size | Various Sizes |
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| Concentration | n/a |
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| Applications | Cell Culture |
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| Other Names | Sonic hedgehog protein;SHH;HHG-1;Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains ;ShhNC ;Sonic hedgehog protein N-product;ShhN;Shh N-terminal processed signaling domains ;ShhNp ;Sonic hedgehog protein 19 kDa product;Shh ;Hhg1; Hhg-1 |
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| Gene, Accession, CAS # | Shh, UniProt: Q62226 |
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| Catalog # | PROTQ62226-2 |
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| Order / More Info | Recombinant Murine Sonic Hedgehog (Shh) Protein from BOSTER BIO |
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| Product Specific References | n/a |
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