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Product Name | Hyaluronic Acid Binding Protein 1, Recombinant, Mouse |
Description | Purity ≥95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: ≤1EU/1ug. Hyaluronan binding protein 1 (HABP1), also known as C1qBP/C1qR and p32, is a ubiquitous acidic glycoprotein that functions in spermatogenesis and as a receptor for proinflammatory molecules. HABP1 is synthesized with a 71 amino acid (aa) N-terminal preproprotein and a 208aa mature region. The 3kD mature mouse HABP1, which contains a MAM33-like sequence, shares 90% and 99% aa sequence identity with human and rat HABP1, respectively. HABP1 assembles into a doughnut shaped trimer, with negatively charged residues asymmetrically distributed on one face lining the channel of the complex. HABP1 can be cleaved by cell surface MMP-14/MT1-MMP, a protease important in angiogenesis and tumor metastasis. Cell surface HABP1 binds a wide range of extracellular molecules, including hyaluronan, vitronectin, complement component C1q, HMW kininogen, and bacterial and viral proteins. With |
Size | 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | Hyaluronic Acid Binding Protein 1, Recombinant, Mouse (Hyaluronan Binding Protein 1, HABP1, C1qBP, C1q-R, Human complement component 1, q subcomponent binding protein) |
Gene, Accession, CAS # | Accession: NP_031599 |
Catalog # | H7980-36 |
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Order / More Info | Hyaluronic Acid Binding Protein 1, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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