| 产品详情 |
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| Product Name | OICR 9429 |
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| Description | High affinity WDR5 antagonist (Kd = 93 nM; IC50 = 64 nM); disrupts WDR5-MLL interaction. Exhibits selectivity for WDR5 over 22 methyltransferases and a panel of kinases, GPCRs, ion channels, and transporters. Reduces viability of acute myeloid leukemia cells in vitro. Also disrupts MLL1-RbBP5 interaction. To request the negative control for OICR 9429, please fill out the OICR 0547 request form on the SGC website.. Purity 98%. MW (observed): 555.59 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide |
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| Gene, Accession, CAS # | CAS: 1801787-56-3 |
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| Catalog # | 5267/10 |
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| Order / More Info | OICR 9429 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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