产品详情 |
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Antigenic Specificity | ITK |
Clone | 18H8 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | ELISA, MA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-ITK Recombinant Antibody (18H8). This product is a mouse antibody that recognizes ITK of human. The antibody 18H8 can be used for immunoassay techniques such as: ELISA, MA. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. The protein Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of ITK to the cell membrane, in the vicinity of the stimulated TCR receptor, where it is phosphorylated by LCK. |
Immunogen | Recombinant SH2 domain of ITK (aa. 222-384) |
Other Names | EMT; LYK; LPFS1; PSCTK2 |
Gene, Accession # | Gene ID: 3702, UniProt: Q08881 |
Catalog # | CBMAB-0652-CN |
Price | |
Order / More Info | ITK Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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