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| Product Name | Sigirr, Recombinant, Mouse, aa1-117, His-SUMO-Tag (Single Ig IL-1-related Receptor) |
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| Description | Purity ~90% (SDS-PAGE). Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its Extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity). Source: Recombinant protein corresponding to aa1-117 from mouse Sigirr, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~28.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Single Ig IL-1R-related molecule, Single immunoglobulin, TIR8 |
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| Gene, Accession, CAS # | SwissProt: Q9JLZ8 |
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| Catalog # | 375296 |
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| Order / More Info | Sigirr, Recombinant, Mouse, aa1-117, His-SUMO-Tag (Single Ig IL-1-related Receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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