产品名称 Otx1, Control Peptide (BSA) from UNITED STATES BIOLOGICAL
产品货号 O8073-05B
产品价格 现货询价,电话:010-67529703
产品规格 1mg
产品品牌 UNITED STATES BIOLOGICAL
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Product NameOtx1, Control Peptide (BSA)
DescriptionSynthetic peptide HPHQLSPMAPSSMAGH (linear) corresponding to aa260-275 of Otx1 and conjugated to BSA. Control peptide for O8073-05. The Otx1 and Otx2 genes are two murine orthologues of the Orthodenticle (Otd) gene in Drosophila. In the developing mouse embryo, both Otx genes are expressed in the rostral head region and in certain sense organs such as the inner ear. Previous studies have shown that mice lacking Otx1 display abnormal patterning of the brain, whereas embryos lacking Otx2 develop without heads. In this study, we examined, at different developmental stages, the inner ears of mice lacking both Otx1 and Otx2 genes. In wild-type inner ears, Otx1, but not Otx2, was expressed in the lateral canal and ampulla, as well as part of the utricle. Ventral to the mid-level of the presumptive utricle, Otx1 and Otx2 were co-expressed, in regions such as the saccule and cochlea. Paint-filled membranous labyrinths of Otx1-/- mutants showed an absence of the lateral semicircular canal, late
Size1mg
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Catalog #O8073-05B
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Order / More InfoOtx1, Control Peptide (BSA) from UNITED STATES BIOLOGICAL
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