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| Product Name | COL4A1, Recombinant, Human, aa1445-1669, His-SUMO-Tag (Collagen alpha-1(IV) Chain) |
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| Description | Purity ~90% (SDS-PAGE). Type IV collagen is the major structural component of glomerular basent membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin. Source: Recombinant protein corresponding to aa1445-1669 from human COL4A1, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~40.9kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P02462 |
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| Catalog # | 372825 |
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| Order / More Info | COL4A1, Recombinant, Human, aa1445-1669, His-SUMO-Tag (Collagen alpha-1(IV) Chain) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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