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Product Name | PTEN, human recombinant |
Description | PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling. Recombinant PTEN is purified by proprietary chromatographic techniques. MW: 80.0 kDa (GST tagged). Purity ≥90% |
Size | 5 µg |
Concentration | 100 µg/ml |
Applications | RUO |
Other Names | Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin homolog, PTEN, MMAC1, TEP1, BZS, MHAM, PTEN1, 10q23del, |
Gene, Accession, CAS # | PTEN, Gene ID: 5728, Accession: P60484 |
Catalog # | 4838-5 |
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Order / More Info | PTEN, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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