| 产品详情 |
| Edit |   |
| Antigenic Specificity | TrxR1 |
| Clone | 19A1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | ELISA: Assay dependent, Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunoprecipitation: 1-2 µL, Western Blot: 1:500-1:5,000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TrxR1 Monoclonal Antibody (19A1). The mammalian thioredoxin reductases (TrxRs) are a family of selenocysteine-containing pyridine nucleotide-disulfide oxidoreductases. All the mammalian TrxRs are homologous to glutathione reductase with respect to primary structure including the conserved redox catalytic site (-Cys-Val-Asn-Val-Gly-Cys-) but distinctively with a C-terminal extension containing a catalytically active penultimate selenocysteine (SeCys) residue in the conserved sequence (-Gly-Cys-SeCys-Gly). TrxR is homodimeric protein in which each monomer includes an FAD prosthetic group, a NADPH binding site and a redox catalytic site. Electrons are transferred from NADPH via FAD and the active-site disulfide to C-terminal SeCys-containing r |
| Immunogen | n/a |
| Other Names | trxR1 |
| Gene, Accession # | Entrez: 7296; Uniprot: Q16881 |
| Catalog # | LF-MA0015 |
| Price | |
| Order / More Info | TrxR1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | PubMed: 24706762 |
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