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| Product Name | MLL1 (KMT2A), Active |
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| Description | 3738-end. MW: 52 kDa. Description: Recombinant human MLL1 (3738-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: Histone-lysine N-methyltransferase 2A also known as mixed-lineage leukemia 1 (MLL1) methylates histone H3 on lysine 4 (H3K4) to promote genome accessibility and transcription. Dysregulation or mutation of the KMT2 family have been found in human cancer, exemplified by the initial discovery of KMT2A rearrangements as causes of |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Methyltransferase Assay |
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| Other Names | [Homo sapiens lysine methyltransferase 2A (KMT2A), transcript variant 2, mRNA; Histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase 2A; lysine methyltransferase 2A; ALL-1; CXXC-type zinc finger protein 7; Myeloid/lymphoid or mixed-lineage leukemia; Myeloid/lymphoid or mixed-lineage leukemia protein 1; Trithorax-like protein; Zinc finger protein HRX] |
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| Gene, Accession, CAS # | MLL1, Gene ID: 4297, Accession: NM_005933.3 |
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| Catalog # | MBS515546 |
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| Order / More Info | MLL1 (KMT2A), Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Rao RC, et al: Hijacked in cancer: the KMT2 (MLL) family of methyltransferases. Nat Rev Cancer. 15 (6): 334-46. 2015. 2. http://www.uniprot.org/uniprot/Q |
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