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| Product Name | MLL3 (KMT2C), Active |
| Description | 4689-end. MW: 51 kDa. Description: Recombinant human MLL3 (4689-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: Histone-lysine N-methyltransferase 2C, also known as mixed-lineage leukemia 2 (MLL3) is the central component of the MLL2/3 complex, a coactivator complex of nuclear receptors involved in transcriptional coactivation. Deletion of the region harboring the MLL3 gene was found to be the most frequently recurrent chromosomal abno |
| Size | 0.005 mg, 0.01 mg |
| Concentration | n/a |
| Applications | Methyltransferase Assay |
| Other Names | [Homo sapiens lysine methyltransferase 2C (KMT2C), mRNA; Histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase 2C; lysine methyltransferase 2C; Homologous to ALR protein; Myeloid/lymphoid or mixed-lineage leukemia protein 3] |
| Gene, Accession, CAS # | MLL3, Gene ID: 58508, Accession: NM_170606.2 |
| Catalog # | MBS515548 |
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| Order / More Info | MLL3 (KMT2C), Active from MYBIOSOURCE INC. |
| Product Specific References | 1. Rao RC, et al: Hijacked in cancer: the KMT2 (MLL) family of methyltransferases. Nat Rev Cancer. 15 (6): 334-46. 2015. 2. Ford DJ, et al: The cancer COMPASS: navigating the functions of MLL complexes in cancer. Cancer Genet. 208 (5):178-91. 2015 3. http://www.uniprot.org/uniprot/Q8NEZ4 |
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