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| Product Name | Recombinant Human Draxin (DRAXIN) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 52kDa. Full Length of Mature Protein: 26-349aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; Neucrin |
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| Gene, Accession, CAS # | DRAXIN, UniProt: Q8NBI3 |
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| Catalog # | RPC23336 |
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| Order / More Info | Recombinant Human Draxin (DRAXIN) from BIOMATIK |
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| Product Specific References | n/a |
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