| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CYLD |
|---|
| Clone | polyclonal |
|---|
| Host Species | Goat |
|---|
| Reactive Species | mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 5 µg/mL, peptide-ELISA: 1:32000, Western Blot: 0.5-1.5 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CYLD Polyclonal Antibody. CYLD is a 956 aa, cytoplasmic, deubiquitinating enzyme belonging to the ubiquitin carboxy-terminal hydrolases (UCH) family of proteins with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains, a proline rich region, a SH3 binding domain and a sequence homology to catalytic domain of UCH. CYLD is identified as a tumor suppressor protein affecting the JNK signaling pathway. CYLD is a negative regulator of TRAF2 and NF-kappa-B signaling pathway and is also known to have receptor-dependent role in regulating the I-kappa-B kinase pathway. It also has a deubiquitinating activity that is directed towards non-Lys-48-linked polyubiquitin chains and TRAP1 is a novel substrate for deubiquitination. Mutat |
|---|
| Immunogen | n/a |
|---|
| Other Names | CYLD; cylindromatosis (turban tumor syndrome) ; 2010013M14Rik; 2900009M21Rik; C130039D01Rik; CDMT; CYLD1; EAC; mKIAA0849; ubiquitin carboxyl-terminal hydrolase CYLD |
|---|
| Gene, Accession # | Entrez: 312937, 74256; Uniprot: Q66H62, Q80TQ2 |
|---|
| Catalog # | PA5-18688 |
|---|
| Price | |
|---|
| Order / More Info | CYLD Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|