| 产品详情 |
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| Antigenic Specificity | Caspase 9 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat, dog |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, FCM, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 9 Polyclonal Antibody. • Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
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| Immunogen | KLH conjugated synthetic peptide derived from human Caspase 9 subunit p35. Immunogen Range: 20-69/416 |
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| Other Names | MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9 |
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| Gene, Accession # | Gene ID: 842, SwissProt: P55211 |
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| Catalog # | bs-0049R |
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| Price | |
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| Order / More Info | Caspase 9 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Wang, G. et al. (2013). Apoptosis. 18(1):28-42. PubMed: 23054084 // Pan, B. et al. (2014) Mol Neurobiol. PubMed: 24510275 // Zhao, Jing, et al. (2014) Basic Res Cardiol 109.5: 1-13. PubMed: 25015734 // Wang, J., et al. (2014) Braz J Med Biol Res. PubMed: 25517918 // Wang, Yu, et al.(2016) Heart Vessels. PubMed: 27639990 // Wang, Yu, et al. (2017) PLoS ONE 12(4):e0173469. PubMed: 28399139 // Huang et al. (2016) Int.J.Mol.Sc. 17. PubMed: 27153056 // Yuan et al. (2016) Int.J.Ophthalmo. 9:505-11. PubMed: 27162720 |
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