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Product Name | PJ 34 hydrochloride |
Description | Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ~1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Displays protective effects against cisplatin -induced kidney injury. Also displays activity at Pim-1 and Pim-2 kinases at higher concentrations (IC50 values are 3.7 and 16 μM respectively). Purity 98%. MW (observed): 331.8 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride |
Gene, Accession, CAS # | CAS: 344458-15-7 |
Catalog # | 3255/10 |
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Order / More Info | PJ 34 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22297980 |
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