| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD117 (c-Kit) |
|---|
| Clone | 104D2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | PerCP-eFluor 710 conjugate |
|---|
| Size | 25 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD117 (c-Kit) Monoclonal Antibody (104D2), PerCP-eFluor 710, eBioscience™. c-Kit, also known as CD117 and stem cell factor receptor, is a 145 kDa transmembrane tyrosine kinase encoded by the c-Kit proto-oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. c-Kit mutations correlate with tumor growth and progression in a variety of cancers including mast cell disease, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma, and lung cancer. Phosphorylation at tyrosine 703 of c-Kit allows binding of |
|---|
| Immunogen | n/a |
|---|
| Other Names | C-Kit, CD117, PBT, SCFR, mast/stem cell growth factor receptor Kit, p145 c-kit, piebald trait protein, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, soluble KIT variant 1, tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, ckit |
|---|
| Gene, Accession # | Entrez: 3815; Uniprot: P10721 |
|---|
| Catalog # | 46-1178-41 |
|---|
| Price | |
|---|
| Order / More Info | CD117 (c-Kit) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 29059238 |
|---|
| 产品资料 |
|
|