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| Product Name | Recombinant Mouse Gremlin 1 / GREM1 Protein (His tag) |
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| Description | MW: 20,710 Da. Purity >97 % as determined by SDS-PAGE. Background: GREM1 belongs to the DAN family. It contains 1 CTCK (C-terminal cystine knot-like) domain. GREM1 is a cysteine knot-secreted protein and acts as an inhibitor in the TGF beta signaling pathway. It inhibits BMP-2, -4, and -7. Inhibition by grem 1 of BMPs in mice allow the expression of fibroblast growth factors (FGFs) 4 and 8 and Sonic hedgehog (SHH) which are necessary for proper limb development. It interacts with SLIT1 and SLIT2 |
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| Size | 0.05 mg, 0.1 mg |
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| Concentration | n/a |
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| Applications | The recombinant mouse GREM1 consists of 171 amino acids and has a calculated molecular mass of 19.7 kDa. The recombinant protein migrates as an approximately 25 kDa band in SDS-PAGE under reducing conditions. |
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| Other Names | [GREM1, Cktsf1b1, Drm] |
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| Gene, Accession, CAS # | GREM1, Gene ID: 23892, Accession: NP_035954.1 |
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| Catalog # | MBS2547211 |
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| Price | |
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| Order / More Info | Recombinant Mouse Gremlin 1 / GREM1 Protein (His tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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