| 产品详情 |
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| Antigenic Specificity | NALP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP1 Polyclonal Antibody. NALP1 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. It contains a caspase recruitment domain (CARD) in addition to a NACHT domain and leucine rich repeat (LRR). This protein interacts strongly with caspase 2 and weakly with caspase 9, as well as with Apaf-1. Transient overexpression of this gene in cultured cells was sufficient to induce apoptosis. NALP1 mRNA and protein expression levels in myeloid leukemia cells are increased following CREB (cAMP-response element binding protein) activation, suggesting that NALP1 may contribute to modulate the response of these cells to pro-inflammatory stimuli. Multiple alternatively spliced transc |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 22861; Uniprot: Q9C000 |
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| Catalog # | PA5-20005 |
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| Price | |
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| Order / More Info | NALP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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