| 产品详情 |
| Edit |   |
| Antigenic Specificity | Caspase 8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot: 1:1000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspase 8 Polyclonal Antibody. Caspase 8 (CASP8) is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases play a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a pro-domain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. Caspase 8 is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of Caspase 8 suggests that it may interact with Fas-interacting protein FADD. Caspase 8 was detect |
| Immunogen | n/a |
| Other Names | Caspase-8, FLICE, MACH, Mch5 |
| Gene, Accession # | Entrez: 841; Uniprot: Q14790 |
| Catalog # | PA1-27990 |
| Price | |
| Order / More Info | Caspase 8 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 产品资料 |
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