| 产品详情 |
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| Antigenic Specificity | ASM |
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| Clone | OTI3H7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ASM Monoclonal Antibody (OTI3H7). Human acid sphingomyelinase (sphingomyelin phosphodiesterase, ASM) is the lysosomal enzyme responsible for the hydrolysis of sphingomyelin to ceramide and phosphocholine. Converts sphingomyelin to ceramide. aSM also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerol-phosphoglycerol. The enzyme is a membrane-associated glycoprotein with a pH optimum of about 4.5 and a subunit molecular mass of about 72 kDa. In addition AtoS M, two other sphingomyelinases have been identified in man, a Mg2+- dependent neutral sphingomyelinase found primarily in brain and a Zn2+-dependent acid sphingomyelinase found primarily in serum. Although it is likely that the acid and neutral s |
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| Immunogen | n/a |
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| Other Names | Sphingomyelin phosphodiesterase (EC:3.1.4.12); Acid sphingomyelinase; aSMase; SMPD1; ASM |
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| Gene, Accession # | Entrez: 6609; Uniprot: P17405 |
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| Catalog # | MA5-26615 |
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| Price | |
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| Order / More Info | ASM Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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