| 产品详情 |
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| Antigenic Specificity | DUSP10 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DUSP10 Polyclonal Antibody. Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and |
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| Immunogen | n/a |
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| Other Names | Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5; |
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| Gene, Accession # | Entrez: 11221, 63953; Uniprot: Q9ESS0, Q9Y6W6 |
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| Catalog # | PA5-15559 |
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| Price | |
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| Order / More Info | DUSP10 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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