| 产品详情 |
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| Product Name | Gedunin |
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| Description | Naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). Decreases ovarian cancer cell proliferation in vitro and may enhance cisplatin -induced reduction in proliferation (CAT.No 3387). Also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Purity 98%. MW (observed): 482.57 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12aS)-5-(Acetyloxy)-1-(3-furanyl)-1,5,6,6a,7,10a,10b,11,12,12a,decahydro-4b,7,7,10a,12a,-pentamethyloxireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione |
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| Gene, Accession, CAS # | Gene ID: 3320, CAS: 2753-30-2 |
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| Catalog # | 3387/1 |
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| Price | |
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| Order / More Info | Gedunin from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20798912, 25915529 |
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| 产品资料 |
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