| 产品详情 |
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| Product Name | AC1903 |
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| Description | A TRPC5 inhibitor (IC50 = 14.7 µM); selective for TRPC5 over TRPC4 and TRPC6 at concentrations up to 100 and 30 µM, respectively; inhibits angiotensin II-induced production of ROS in wild-type podocytes and podocytes expressing a mutant AT1 receptor; suppresses proteinuria as well as reduces pseudocyst formation and podocyte loss in an AT1 receptor transgenic rat model of kidney disease at 50 mg/kg twice per day; decreases the rate of proteinuria and prevents progression in a Dahl salt-sensitive rat model of FSGS |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AC-1903 TRPC-5 TRPC-4 TRPC-6 HEK-293 |
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| Gene, Accession, CAS # | CAS: 831234-13-0 |
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| Catalog # | 25324-10 |
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| Price | |
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| Order / More Info | AC1903 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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