| 产品详情 |
| Edit |   |
| Antigenic Specificity | EGR2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | ChIP, IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to EGR2. E3 SUMO-protein ligase EGR2 belongs to the EGR C2H2-type zinc-finger protein family. EGR2 is a sequence-specific DNA-binding transcription factor and binds to two specific DNA sites located in the promoter region of HOXA4. EGR2 helps SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in EGR2 are a cause of congenital hypomyelination neuropathy (CHN), of Charcot-Marie-Tooth disease type 1D (CMT1D), and of Dejerine-Sottas syndrome (DSS). |
| Immunogen | C-terminal region of human EGR2 |
| Other Names | E3 SUMO-protein ligase EGR2, AT591, Early growth response protein 2, Zinc finger protein Krox-20, EGR-2, KROX20 |
| Gene, Accession # | UniProt: P11161 |
| Catalog # | orb131906 |
| Price | |
| Order / More Info | EGR2 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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