产品详情 |
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Antigenic Specificity | EGR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | ChIP, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to EGR2. E3 SUMO-protein ligase EGR2 belongs to the EGR C2H2-type zinc-finger protein family. EGR2 is a sequence-specific DNA-binding transcription factor and binds to two specific DNA sites located in the promoter region of HOXA4. EGR2 helps SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in EGR2 are a cause of congenital hypomyelination neuropathy (CHN), of Charcot-Marie-Tooth disease type 1D (CMT1D), and of Dejerine-Sottas syndrome (DSS). |
Immunogen | C-terminal region of human EGR2 |
Other Names | E3 SUMO-protein ligase EGR2, AT591, Early growth response protein 2, Zinc finger protein Krox-20, EGR-2, KROX20 |
Gene, Accession # | UniProt: P11161 |
Catalog # | orb131906 |
Price | |
Order / More Info | EGR2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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