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| Product Name | Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), partial |
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| Description | 22-561. Fragment at the N-terminal, provide the first complete extracellular domain. MW: 62.37kD. Purity >90% as determined by SDS-PAGE. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a st cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signali |
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| Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.1 mg (Yeast), 0.2 mg (Yeast), 0.5 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38] |
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| Gene, Accession, CAS # | LGR5, Gene ID: 8549, Accession: NP_001264155.1 |
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| Catalog # | MBS1247111 |
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| Order / More Info | Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), partial from MYBIOSOURCE INC. |
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| Product Specific References | Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily.McDonald T., Wang R., Bailey W., Xie G., Chen F., Caskey C.T., Liu Q.Biochem. Biophys. Res. Commun. 247:266-270(1998) Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.Hsu S.Y., Liang S.-G., Hsueh A.J.W.Mol. Endocrinol. 12:1830-1845(1998) Alternatively spli |
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