| 产品详情 |
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| Antigenic Specificity | SGPP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, equine, guinea pig, human, mouse, nonhuman primate, rabbit, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SGPP2 Polyclonal Antibody. Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/Gprotein- coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family whichplay a role in attenuating intracellular S1P sig |
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| Immunogen | n/a |
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| Other Names | Sphingosine-1-phosphate phosphatase 2, FLJ39004, SPP2 |
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| Gene, Accession # | Entrez: 0, 100060934, 100337041, 100357833, 100731261, 130367, 301543, 433323; Uniprot: Q810K3, Q8IWX5 |
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| Catalog # | PA5-42767 |
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| Price | |
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| Order / More Info | SGPP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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