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| Product Name | Recombinant Rat Tie2 / TEK Protein (Fc tag) |
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| Description | Purity >95 % as determined by SDS-PAGE. Background: TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transductio |
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| Size | 0.1 mg, 0.2 mg |
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| Concentration | n/a |
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| Applications | The recombinant rat TEK/Fc is a disulfide-linked homodimer. The reduced monomer comprises 962 amino acids and predicts a molecular mass of 108 kDa. The apparent molecular mass of the rat TEK/Fc monomer is approximately 120-130 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
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| Other Names | [Tie-2, Tie2] |
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| Gene, Accession, CAS # | Tie2 / TEK, Gene ID: 89804, Accession: NP_001099207.1 |
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| Catalog # | MBS2547479 |
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| Order / More Info | Recombinant Rat Tie2 / TEK Protein (Fc tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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