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| Antigenic Specificity | AIM2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 488 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AIM2 Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell d |
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| Immunogen | KLH conjugated synthetic peptide derived from mouse AIM2. Immunogen Range: 250-300/354 |
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| Other Names | Gm1313; Ifi210; Interferon-inducible protein AIM2; Interferon-inducible protein 210; Ifi-210; Interferon-inducible protein p210; Aim2 |
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| Gene, Accession # | Gene ID: 383619, SwissProt: Q91VJ1 |
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| Catalog # | bs-5986R-A488 |
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| Price | |
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| Order / More Info | AIM2 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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