| 产品详情 |
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| Product Name | CC-930 |
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| Description | A potent JNK inhibitor (IC50s = 61, 7, and 6 nM for JNK1, JNK2, and JNK3, respectively); selective for MAP kinases; selective for JNKs over other MAPK family proteins (IC50s = 3,400 and 480 nM for p38α and ERK1, respectively); inhibits JNK in a cell lysate assay (IC50 = 200 nM); blocks phosphorylation of c-Jun in LPS-stimulated human PBMCs; inhibits TNF-α production induced by LPS when administered to rats at doses of 10 and 30 mg/kg; reduces lung fibrosis in a mouse pulmonary fibrosis model, |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tanzisertib |
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| Gene, Accession, CAS # | CAS: 899805-25-5 |
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| Catalog # | 22466-1 |
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| Price | |
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| Order / More Info | CC-930 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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