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| Product Name | Recombinant Human Transmembrane protein 59 (TMEM59) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 35.5kDa. Full Length of Mature Protein: 37-323aa. C-terminal 10xHis-tagged. Homo sapiens (Human). Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Liver membrane-bound protein |
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| Gene, Accession, CAS # | TMEM59, UniProt: Q9BXS4 |
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| Catalog # | RPC20762 |
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| Order / More Info | Recombinant Human Transmembrane protein 59 (TMEM59) from BIOMATIK |
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| Product Specific References | n/a |
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