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Product Name | Recombinant Human Agouti-related protein (AGRP), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 32.7kDa. Partial: 83-132aa. N-terminal GST-tagged. Homo sapiens (Human). Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin syst. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.5 Publications |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | AGRP, UniProt: O00253 |
Catalog # | RPC24090 |
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Order / More Info | Recombinant Human Agouti-related protein (AGRP), partial from BIOMATIK |
Product Specific References | n/a |
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