| 产品详情 |
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| Product Name | Recombinant Mouse Glucagon receptor (Gcgr), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 15.8kDa. Extracellular Domain: 27-143aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger syst. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gcgr, UniProt: Q61606 |
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| Catalog # | RPC24678 |
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| Order / More Info | Recombinant Mouse Glucagon receptor (Gcgr), partial from BIOMATIK |
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| Product Specific References | n/a |
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