| 产品详情 |
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| Product Name | Recombinant Rat Inducible T-cell costimulator (Icos), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 18.1kDa. Extracellular Domain: 21-145aa. N-terminal 6xHis-tagged. Rattus norvegicus (Rat). Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity). |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Activation-inducible lymphocyte immunomediatory molecule; CD_antigen: CD278 |
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| Gene, Accession, CAS # | Icos, UniProt: Q9R1T7 |
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| Catalog # | RPC23731 |
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| Price | |
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| Order / More Info | Recombinant Rat Inducible T-cell costimulator (Icos), partial from BIOMATIK |
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| Product Specific References | n/a |
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| 产品资料 |
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