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| Product Name | Recombinant Rabbit Histidine triad nucleotide-binding protein 1 (HINT1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 17.6kDa. Full Length of Mature Protein: 2-126aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Oryctolagus cuniculus (Rabbit). Functions as enzyme, and as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex (By similarity). Hydrolyzes purine nucleotide phosphoramidates, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon- (N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, lysyl-GMP (GMP-N-epsilon- (N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Adenosine 5'-monophosphoramidase; P13.7 |
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| Gene, Accession, CAS # | HINT1, UniProt: P80912 |
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| Catalog # | RPC20602 |
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| Order / More Info | Recombinant Rabbit Histidine triad nucleotide-binding protein 1 (HINT1) from BIOMATIK |
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| Product Specific References | n/a |
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