| 产品详情 |
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| Antigenic Specificity | SESN1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SESN1 Polyclonal Antibody. This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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| Immunogen | n/a |
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| Other Names | PA26, SEST1 |
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| Gene, Accession # | Entrez: 140742, 27244, 294518; Uniprot: P58006, Q9Y6P5 |
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| Catalog # | PA5-50132 |
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| Price | |
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| Order / More Info | SESN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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