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| Product Name | Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A (APOBEC3A) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 39kDa. Full Length: 1-199aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Phorbolin-1 |
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| Gene, Accession, CAS # | APOBEC3A, UniProt: P31941 |
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| Catalog # | RPC20916 |
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| Order / More Info | Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A (APOBEC3A) from BIOMATIK |
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| Product Specific References | n/a |
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