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| Product Name | DCK, 1-260aa, Human, His tag, E Coli |
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| Description | MW: 34.6 kDa (296aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. DCK is a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant nucleoside analogues. This protein is responsible for the 5-phosphorylation of purine and pyrimidine deoxynucleosides to the corresponding monophosphates using ATP or uTP as phosphate donors. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increas |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Deoxycytidine kinase; MGC117410; MGC138632; Deoxycytidine kinase] |
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| Gene, Accession, CAS # | DCK, Gene ID: 1633, Accession: NP_000779 |
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| Catalog # | MBS203534 |
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| Order / More Info | DCK, 1-260aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Radu CG., et al. (2010) Proc Natl Acad Sci u S A. 107 (12):5551-6; Ribeiro R., et al. (2007) J Pharmacol Exp Ther. 323 (3):935-45; |
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