| 产品详情 |
| Edit |   |
|---|
| Product Name | EPZ-5676 |
|---|
| Description | MW: 562.71. Purity ≥98% by HPLC. Background: A potent and selective inhibitor of DOT1L methyltransferase (Ki = 80 pM). EPZ-5676 displays 37,000-fold selectivity over all other tested methyltransferases. It inhibits H3K79 methylation and MLL-fusion target gene expression and displays potent cell killing selective for acute leukemia lines bearing MLL translocations. |
|---|
| Size | 1 mg, 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol ] |
|---|
| Gene, Accession, CAS # | CAS: 1380288-87-8 |
|---|
| Catalog # | MBS842855 |
|---|
| Price | |
|---|
| Order / More Info | EPZ-5676 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|