| 产品详情 |
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| Antigenic Specificity | Lamin-A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:1,000, Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin-A Polyclonal Antibody. Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone. |
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| Immunogen | n/a |
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| Other Names | 70 kDa lamin, cardiomyopathy, dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin A/C-like 1, LDP1, LFP, LGMD1B, limb girdle muscular dystrophy 1B (autosomal dominant), LMN1, LMNC, LMNL1, prelamin-A/C, PRO1, progeria 1 (Hutchinson-Gilford type), renal carcinoma antigen NY-REN-32 |
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| Gene, Accession # | Entrez: 16905, 4000; Uniprot: P02545, P48678 |
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| Catalog # | A303-433A |
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| Price | |
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| Order / More Info | Lamin-A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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