产品详情 |
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Antigenic Specificity | Lamin A |
Clone | 133A2 |
Host Species | Mouse |
Reactive Species | bovine, canine, human, mouse, rat |
Isotype | IgG3 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1:100 - 1:200, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 1:100 - 1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lamin A Monoclonal Antibody (133A2). Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 16905, 4000, 404144, 480124, 60374; Uniprot: P02545, P48678, P48679 |
Catalog # | MA1-06101 |
Price | |
Order / More Info | Lamin A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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