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Product Name | Recombinant Human Secreted Ly-6/uPAR-related protein 1 (SLURP1) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 8.9kDa. Full Length of Mature Protein: 23-103aa. tag-Free. Homo sapiens (Human). Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca2+ signaling. Seems to have a immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | ARS component B; ARS (component B)-81/S; Anti-neoplastic urinary protein |
Gene, Accession, CAS # | SLURP1, UniProt: P55000 |
Catalog # | RPC22020 |
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Order / More Info | Recombinant Human Secreted Ly-6/uPAR-related protein 1 (SLURP1) from BIOMATIK |
Product Specific References | n/a |
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