| 产品详情 |
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| Product Name | TW-37 |
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| Description | TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 µM, 1.11 µM and 0.26 µM, respectively. TW-37 inhibits the growth of a broad range of cancer cells (such as breast, prostate, lymphoma, and pancreatic cancer), since it induces S-phase cell cycle arrest with regulation of several important cell cycle related genes, including p27, p57, E2F-1, cdc25A, CDK4, cyclin A, cyclin D1 and cyclin E. MW: 573.7. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-(2-tert-butylphenyl)sulfonylphenyl]-2,3,4-trihydroxy-5-[(2-propan-2-ylphenyl)methyl]benzamide |
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| Gene, Accession, CAS # | CAS: 877877-35-5 |
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| Catalog # | 2789-5 |
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| Order / More Info | TW-37 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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