| 产品详情 |
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| Product Name | GSK2578215A |
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| Description | Potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant. Purity 99%. MW (observed): 399.42 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide |
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| Gene, Accession, CAS # | CAS: 1285515-21-0 |
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| Catalog # | 4629/25 |
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| Price | |
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| Order / More Info | GSK2578215A from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23916833, 24904275, 25118928, 26384650, 26646749, 26758690, 27503089 |
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