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| Product Name | Recombinant Human 3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 42.8kDa. Full Length of Mature Protein: 2-261aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 17-beta-hydroxysteroid dehydrogenase 10 (EC:1.1.1.51); 17-beta-HSD 103-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC:1.1.1.178)3-hydroxyacyl-CoA dehydrogenase type IIEndoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2Short chain dehydrogenase/reductase family 5C member 1Short-chain type dehydrogenase/reductase XH98G2Type II HADH |
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| Gene, Accession, CAS # | HSD17B10, UniProt: Q99714 |
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| Catalog # | RPC23525 |
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| Order / More Info | Recombinant Human 3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) from BIOMATIK |
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| Product Specific References | n/a |
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