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| Product Name | Recombinant Human Ig gamma-1 chain C region (IGHG1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 68.5kDa. Full Length of BC014667: 1-479aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- (D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Ig gamma-1 chain C region; Ig gamma-1 chain C region EU2; Ig gamma-1 chain C region KOL1; Ig gamma-1 chain C region NIE |
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| Gene, Accession, CAS # | IGHG1, UniProt: P01857 |
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| Catalog # | RPC21502 |
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| Order / More Info | Recombinant Human Ig gamma-1 chain C region (IGHG1) from BIOMATIK |
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| Product Specific References | n/a |
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