| 产品详情 |
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| Product Name | GW-5074 |
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| Description | MW: 520.9. Purity 98% (TLC); NMR (Conforms). c-Raf1 inhibitorPotent and selective p38 MAP kinase inhibitor XYZ XYZ (IC50=32 nM). Does not inhibit p38 up to 10 M. Inhibition is reversible and noncompetitive with ATP and substrate. Reversibly inhibits myoblast differentiation. Cell permeable.Scientific Background: Specific inhibitor of cRaf-1 kinase (IC50=9 nM). Acts at ≥ 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displa |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [JX-401 ; 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine; 3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one] |
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| Gene, Accession, CAS # | CAS: 220904-83-6 |
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| Catalog # | MBS515012 |
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| Order / More Info | GW-5074 from MYBIOSOURCE INC. |
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| Product Specific References | 1. Y Friedmann et al. Mol. Pharmacol. 2006 70:1395 |
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