| 产品详情 |
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| Product Name | Recombinant Human Carbonyl reductase [NADPH] 1 (CBR1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 57.2kDa. Full Length of Mature Protein: 2-277aa. N-terminal GST-tagged. Homo sapiens (Human). NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 15-hydroxyprostaglandin dehydrogenase [NADP (+)] (EC:1.1.1.197)NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductaseProstaglandin-E (2) 9-reductase (EC:1.1.1.189)Short chain dehydrogenase/reductase family 21C member 1 |
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| Gene, Accession, CAS # | CBR1, UniProt: P16152 |
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| Catalog # | RPC21035 |
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| Order / More Info | Recombinant Human Carbonyl reductase [NADPH] 1 (CBR1) from BIOMATIK |
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| Product Specific References | n/a |
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