| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Sheep Interleukin-12 subunit beta (IL12B) |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 36.5kDa. Full Length of Mature Protein: 23-327aa. N-terminal 6xHis-tagged. Ovis aries (Sheep). Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates mory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Cytotoxic lymphocyte maturation factor 40KDA subunit; CLMF p40IL-12 subunit p40 |
|---|
| Gene, Accession, CAS # | IL12B, UniProt: P68220 |
|---|
| Catalog # | RPC24741 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Sheep Interleukin-12 subunit beta (IL12B) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|