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| Product Name | Recombinant Sheep Tumor necrosis factor (TNF), Partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 44.2kDa. Partial: 78-234aa. N-terminal GST-tagged. Ovis aries (Sheep). Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cachectin; TNF-alphaTumor necrosis factor ligand superfamily member 2; TNF-a |
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| Gene, Accession, CAS # | TNF, UniProt: P23383 |
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| Catalog # | RPC22143 |
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| Order / More Info | Recombinant Sheep Tumor necrosis factor (TNF), Partial from BIOMATIK |
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| Product Specific References | n/a |
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